Synergistic positive feedback underlying seizure initiation
R. Graham, R. Ryley Parrish, Laura Alberio, Emily L. Johnson, Laura J. Owens, Andrew J. Trevelyan
The paper identifies synergistic positive feedback mechanisms that drive seizure initiation and shows that an optogenetic stimulation paradigm can delay epileptic activity.
bioRxiv · Feb 28, 2021 · PreprintNeuroscience