Decoding antibiotic modes of action from multimodal cellular responses
J. Hesse, Dominik Schum, Laura Leidel, Leonard R. Gareis, Jennifer E. Herrmann, R. P. A. Müller, Stephan A. Sieber
This study develops MAPPER, a framework for predicting antibiotic modes of action using proteomics and chemical data, showing it can classify mechanisms and detect novel compounds.
bioRxiv · Apr 2, 2026 · PreprintBioinformatics