Jennifer E. Herrmann

This study identifies nitroxoline's antibacterial mechanism as pathogen-driven reactivation of its metabolites through iron deprivation in uropathogens.

This study develops MAPPER, a framework for predicting antibiotic modes of action using proteomics and chemical data, showing it can classify mechanisms and detect novel compounds.

This study isolates and characterizes two new compounds from myxobacteria, elucidates their structures, and evaluates their antimicrobial activity against Gram-positive bacteria.

This study identifies chlorotonils as potent anti-Mtb agents and shows resistance is mediated by MmpR5-MmpL5.

This paper discovers first-in-class 1,2,4-triazole-based non-nucleoside inhibitors of MraY with broad-spectrum antibacterial activity against multiple bacterial species.

This study profiles cystobactamids' off-target effects in eukaryotes, showing safety, superoxide reduction, and SCARB1 inhibition with therapeutic potential.