Adult Hox gene expression promotes periosteal stem cell maintenance and mediates reprogramming in a regionally restricted manner
Kevin Leclerc, Lindsey H. Remark, Malissa Ramsukh, Anne Marie Josephson, Sophie M. Morgani, Laura Palma, Paulo EL Parente, Sooyeon Lee, Emma Muiños-López, Philipp Leucht
This study shows Hox genes maintain periosteal stem cells in an uncommitted state and mediate region-specific reprogramming in adult bone.
bioRxiv · May 15, 2022 · PreprintMolecular Biology