Sex-specific developmental phenotypes and their response to neonatal Dyrk1a reduction in the Ts65Dn Down syndrome mouse model
Alyssa Duerst, Laura E. Hawley, Linnea Johnson, Zaina Obeid, Laura Snellenberger, Andrew Folz, Charles R. Goodlett, Randall J. Roper
This study examines sex-specific developmental effects of neonatal Dyrk1a reduction in Ts65Dn Down syndrome mice, finding partial improvements in some phenotypes but not all.
bioRxiv · Jul 17, 2026 · PreprintGenetics