Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons
Donna Cosgrove, Laura Whitton, Laura Fahey, Pilib Ó Broin, Gary J Donohoe, Derek W. Morris
The paper identifies genes regulated by MEF2C during neurodevelopment that are associated with schizophrenia, intelligence, and neurodevelopmental disorders, with different genetic variants affecting distinct cell types and phenotypes.
Human Molecular Genetics · Sep 22, 2020Peer-reviewedGenomics