BioinformaticsbioRxivPreprint
S3R: Modeling spatially varying associations with Spatially Smooth Sparse Regression
Xinyu Zhou, Pengtao Dang, Xiao Wang…·Sha Cao
S3R models spatially varying associations in spatial transcriptomics data by estimating location-specific coefficients with structured sparsity and smoothness penalties, showing effectiveness in synthetic and real datasets.