Teresa A. Zimmers

This paper introduces a dual-contrast microCT protocol to track tumor growth, metastasis, and cachexia in murine PDAC models over time.

S3R models spatially varying associations in spatial transcriptomics data by estimating location-specific coefficients with structured sparsity and smoothness penalties, showing effectiveness in synthetic and real datasets.

This study identifies population-specific transcriptional changes in skeletal muscle myonuclei during pancreatic cancer cachexia, revealing distinct gene activation patterns rather than uniform upregulation of cachexia mediators.

This study shows that liver-derived Yap1 activation during organ repair induces systemic catabolism and muscle loss, similar to cancer cachexia.

This study identifies circulating protein biomarkers associated with pancreatic cancer cachexia using serum samples and correlates them with clinical measures.