Computational Modeling of Motor-Driven Extension of Microtubule Bundles in Axons
Donghyun Yim, Laurel Patterson, Daniel M. Suter, Kyle E. Miller, Taeyoon Kim
This study uses a computational model to show that intermediate cross-linking density and microtubule stiffness maximize axonal outgrowth by balancing buckling resistance and mechanical load.
bioRxiv · Sep 25, 2025 · PreprintBiophysics