Author

Lauren A. Devito

Western University

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfie WearniD· 1 shared Alfonso Fajardo-Valdez· 1 shared Alycia M CrooksiD· 1 shared Étienne AumontiD· 1 shared Flávio H. BeraldoiD· 1 shared Gary R. TurneriD· 1 shared Geoffrey N. Ngo· 1 shared Hayley R.C. ShanksiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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Alfie WearnORCID

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1 paper

Recent·Most cited

Cholinergic synaptic plasticity shapes resilience and vulnerability to tau

Kate M. Onuska, Hayley R.C. Shanks, Lauren A. Devito, Qi Qi, Alycia M Crooks, Liliana Germán-Castelán, Geoffrey N. Ngo, Roy A.M. Haast, Tallulah S. Andrews, Kayla M. Williams, Flávio H. Beraldo, Ting Qiu, Alfonso Fajardo-Valdez, Jordana Remz, Alfie Wearn, , Taylor W. Schmitz

The paper shows that cholinergic synaptic plasticity, specifically VAChT responses to tau, correlates with cognitive resilience in presymptomatic AD.

bioRxiv · May 27, 2025 · PreprintNeuroscience