Author

Flávio H. Beraldo

Western UniversityORCID 0000-0001-7638-2007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Assay:imaging· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Marco A. M. PradoiD· 3 shared Lisa M. SaksidaiD· 2 shared Timothy J. BusseyiD· 2 shared Alfie WearniD· 1 shared Alfonso Fajardo-Valdez· 1 shared Aline Silva de MirandaiD· 1 shared Alycia M CrooksiD· 1 shared Anoosha AttaraniD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Marco A. M. PradoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cholinergic synaptic plasticity shapes resilience and vulnerability to tau

Kate M. Onuska, Hayley R.C. Shanks, Lauren A. Devito, Qi Qi, Alycia M Crooks, Liliana Germán-Castelán, Geoffrey N. Ngo, Roy A.M. Haast, Tallulah S. Andrews, Kayla M. Williams, Flávio H. Beraldo, Ting Qiu, Alfonso Fajardo-Valdez, Jordana Remz, Alfie Wearn, , Taylor W. Schmitz

The paper shows that cholinergic synaptic plasticity, specifically VAChT responses to tau, correlates with cognitive resilience in presymptomatic AD.

bioRxiv · May 27, 2025 · PreprintNeuroscience

Presymptomatic neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model of synucleinopathy

Stéphanie Tullo, Aline Silva de Miranda, Esther del Cid‐Pellitero, Mei Peng Lim, Daniel Gallino, Anoosha Attaran, Raihaan Patel, Vladislav Novikov, Megan Park, Flávio H. Beraldo, Wen Luo, Irina Shlaifer, Thomas M. Durcan, Timothy J. Bussey, Lisa M. Saksida, , M. Mallar Chakravarty

This study identifies neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model, showing early cognitive deficits and brain atrophy linked to prion-like spread of misfolded alpha-synuclein.

bioRxiv · Oct 12, 2022 · PreprintNeuroscience

Measuring nonapoptotic caspase activity with a transgenic reporter in mice

PETER J. NICHOLLS, Thomas F. Pack, Nikhil M. Urs, Sunil Kumar, Yang Zhou, Gabriel Ichim, Joshua D. Ginzel, Gábor Turu, Evan Calabrese, Wendy L. Roberts, Ping Fan, Valeriy G. Ostapchenko, Monica S. Guzman Lenis, Flávio H. Beraldo, Jiřı́ Hatina, , Marc G. Caron

The paper develops a transgenic mouse model with a fluorescent caspase activity reporter to quantify nonapoptotic caspase activity in rodent brains and demonstrates its use in studying neurophysiological and stress-related effects.

eNeuro · Sep 1, 2022Peer-reviewedNeuroscience