Author

Lauren E. Perley

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Harvey J. KlimaniD· 2 shared Jane O’BryaniD· 2 shared Kimberly C. OlneyiD· 2 shared Melissa A. WilsoniD· 2 shared Michelle SilasiiD· 2 shared Tanya N. PhungiD· 2 shared Adrianna SorianoiD· 1 shared Amy M. BremaniD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Harvey J. KlimanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Validation study for noninvasive single-cell-based prenatal genetic testing

Michelle Bellair, Elisabete Amaral, Mason Ouren, Cameron Roark, Jae‐Weon Kim, April O’Connor, Adrianna Soriano, Margaret L. Schindler, Ronald J. Wapner, Joanne L. Stone, Nicola Francesco Tavella, Audrey Anne Merriam, Lauren E. Perley, Amy M. Breman, Arthur L. Beaudet

This study validates a noninvasive prenatal genetic test using single trophoblast analysis, showing high concordance with CVS/amniocentesis for aneuploidy and deletions/duplications.

medRxiv · Aug 29, 2023 · PreprintGenetic & Genomic Medicine

Sex differences in early and term placenta are conserved in adult tissues

Kimberly C. Olney, Seema B. Plaisier, Tanya N. Phung, Michelle Silasi, Lauren E. Perley, Jane O’Bryan, Lucia Ramirez, Harvey J. Kliman, Melissa A. Wilson

The paper identifies sex differences in gene expression in placenta at different pregnancy stages and shows these differences are conserved in adult tissues.

Biology of Sex Differences · Dec 22, 2022Peer-reviewedGenomics

X chromosome inactivation in the human placenta is patchy and distinct from adult tissues

Tanya N. Phung, Kimberly C. Olney, Brendan J. Pinto, Michelle Silasi, Lauren E. Perley, Jane O’Bryan, Harvey J. Kliman, Melissa A. Wilson

The paper examines X chromosome inactivation in the human placenta and finds it is patchy, differing from the mosaic pattern observed in adult tissues.

Human Genetics and Genomics Advances · May 23, 2022Peer-reviewedGenomics