Author

Lauren M. Carito

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Lee Prinzen· 1 shared Amr OmeriD· 1 shared Benjamin J. AndreoneiD· 1 shared Elga Morrison· 1 shared Smita Jagtap· 1 shared Stefan I. McDonough· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Alexander Lee Prinzen

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJan 30, 2026

Increased CD33 levels tune activation and function of iinduced human microglial cells through inhibition of the TREM2 pathway

Amr Omer, Smita Jagtap, Elga Morrison…·Benjamin J. Andreone

This study shows that CD33 modulates microglial function in Alzheimer's disease by inhibiting TREM2 activation, with reduced CD33 increasing amyloid beta uptake and TREM2 activity.

DOI 10.64898/2026.01.28.701050

humanproteomics

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