Multi-attribute characterisation of mRNA via MazF endoribonuclease and LC-MS workflows
Emma P Welbourne, Gareth R. Owen, Lauren P Wright, Sara Maria David Trabulo, Zoltan Kis, Mark J. Dickman
The paper presents two LC-MS workflows using MazF endoribonuclease to characterise mRNA sequence identity, 5' capping efficiency, and poly(A) tail length and heterogeneity.
bioRxiv · Sep 24, 2026 · PreprintBiochemistry