EBV Type 1 versus Type 2: A determinant of NK cell anti-tumor activity in Burkitt lymphoma
Catherine Suzanne Forconi, Lauren Shumate, Zachary J. Racenet, Viriato M’Bana, Cliff I. Oduor, Angela M. Matta, Jeni Melo, Peter O. Oluoch, Boaz Odwar, Juliana A. Otieno, Terry A. Vik, Festus N'juguna, Ann W. Kinyua, Jeffrey A. Bailey, Christian Münz, Ann Marie Moormann
This study compares ADCC activity of CD56neg and CD56dim NK cells against EBV-type 1 and 2 Burkitt lymphoma cells, finding EBV-T2 cells are more susceptible to direct cytotoxicity.
bioRxiv · Feb 10, 2026 · PreprintImmunology