Inhibition of itch by neurokinin 1 receptor (Tacr1) -expressing ON cells in the rostral ventromedial medulla
Taylor Follansbee, Dan T. Domocos, Eileen K. Nguyen, Amanda Nguyen, Aristea Bountouvas, Lauren Velasquez, Mirela Iodi Carstens, Keiko Takanami, Sarah E. Ross, Earl E. Carstens
This study investigates the role of Tacr1-expressing ON cells in the RVM in modulating pruriceptive transmission, finding they inhibit itch despite being pronociceptive.
eLife · Aug 5, 2022Peer-reviewedNeuroscience