Fetal estrogens are not involved in sex determination but critical for early ovarian differentiation.
Geneviève Jolivet, Nathalie Daniel-Carlier, Erwana Harscoët, Éloïse Airaud, Aurélie Dewaele, Cloé Pierson, Frank Giton, Laurent Boulanger, Nathalie Daniel, Béatrice Mandon‐Pepin, Maëlle Pannetier, Éric Pailhoux
The paper shows that fetal estrogen production is not required for ovarian determination but is essential for ovarian development and follicle formation in rabbits.
Endocrinology · Oct 6, 2021Peer-reviewedDevelopmental Biology