Frank Giton

This paper develops a mass spectrometry-based method to track steroid dynamics in intact mice, revealing tissue-specific metabolism patterns of sex steroids.

The paper identifies a biphasic gene regulatory network in rat pituitary gonadotropes that controls the preovulatory hormone surge, showing FSH surge is driven by dynamic Fshb transcription rather than Lhb upregulation.

This study shows that reducing minipubertal gonadotropin levels in mice extends reproductive lifespan but accelerates ovarian follicle depletion without affecting early fertility.

This study shows that absence of estrogen in male rabbits leads to reduced fertility, lower sperm count, and increased flagellar defects in sperm.

The paper shows that fetal estrogen production is not required for ovarian determination but is essential for ovarian development and follicle formation in rabbits.