Intrinsically disordered regions influence protein motif usage in Drosophila Ubx and AbdA Hox proteins
Corinne Maurel-Zaffran, Ilan Edelstein, Laurianne Michel, Meiggie Macchi, Nathalie Caruso, Andrew J. Saurin, Yaakov Levy, Yacine Graba
The paper shows that intrinsically disordered regions in Drosophila Hox proteins affect the usage of conserved motifs near the homeodomain through context-dependent intramolecular interactions.
bioRxiv · Oct 12, 2026 · PreprintDevelopmental Biology