Author

Laurie Holmes

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Brian R. Granger· 1 shared Gina Vicente· 1 shared Justin Abreu· 1 shared Lisa GreeniD· 1 shared Mark FlehartyiD· 1 shared Maura CostelloiD· 1 shared Michael Dasilva· 1 shared Niall J. LennoniD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Brian R. Granger

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1 paper

Recent·Most cited

Characterization and remediation of sample index swaps by non-redundant dual indexing on massively parallel sequencing platforms

Maura Costello, Mark Fleharty, Justin Abreu, Yossi Farjoun, Steven Ferriera, Laurie Holmes, Brian R. Granger, Lisa Green, Tom Howd, Tamara Mason, Gina Vicente, Michael Dasilva, Wendy Brodeur, Timothy DeSmet, Sheila Dodge, , Stacey Gabriel

The paper characterizes index swapping on Illumina sequencers and proposes dual indexing to mitigate its effects, showing varying swap rates across methods and sequencers.

BMC Genomics · May 8, 2018Peer-reviewedGenomics