Haploinsufficiency of the psychiatric risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms
Niels Haan, Laura J Westacott, Jenny Carter, Michael John Owen, William P Gray, Jérémy Hall, Lawrence S Wilkinson
This study shows that Cyfip1 haploinsufficiency disrupts hippocampal neurogenesis by affecting microglial apoptosis and actin dynamics in adult-born neurons.
bioRxiv · Jun 6, 2020 · PreprintNeuroscience