NETSseq Reveals Inflammatory and Aging Mechanisms in Distinct Cell Types Driving Cerebellar Decline in Ataxia Telangiectasia
Giuliano Giuseppe Stirparo, Xiao Xu, Thompson Toni, Keith J. Page, Jenna R. M. Harvey, David Cadwalladr, Jason M.K. Lawrence, Russell Burley, Joel Juvvanapudi, Roberts Megan, Daniel F. Barker, Victoria J. Mulligan, Sherlock Chloe, Marina Lizio, Louisa A. Christie, , Lee A. Dawson
This study uses NETSseq to analyze cerebellar tissue from A-T patients and controls, identifying cell-type-specific gene dysregulation and aging signatures linked to neurological decline.
bioRxiv · May 13, 2025 · PreprintNeuroscience