Author

Lei Shang

Primary ORCID profile (0000-0001-7285-4361 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Lei ShangiD1 paper · Pfizer (United States)

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexander Antipenko· 1 shared Alexandre BolzeiD· 1 shared Aurelie Cobat· 1 shared Aziz Belkadi· 1 shared Bertrand BoissoniD· 1 shared Jean-Laurent Casanova· 1 shared Laurent AbeliD· 1 shared Quentin B Vincent· 1 shared

Activity by Year

2015-2015 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Alexander Antipenko

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1 paper

Recent·Most cited

Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants

Aziz Belkadi, Alexandre Bolze, Yuval Itan, Aurelie Cobat, Quentin B Vincent, Alexander Antipenko, Lei Shang, Bertrand Boisson, Jean-Laurent Casanova, Laurent Abel

This study compares whole-genome sequencing (WGS) and whole-exome sequencing (WES) in six individuals, finding WGS more effective at detecting coding variants, particularly SNVs, with fewer false positives.

Proceedings of the National Academy of Sciences · Apr 28, 2015Peer-reviewedGenetics