A myosin filament cage drives multiple aspects of mitosis unique to cells dividing within a polarized epithelium
Muhammad Sulaiman Yousafzai, Kirsten Remmert, Anjelika Gasilina, Grace Perry, Lelia Boley, Chris Alexander, António T. Pedrosa, Dillon C. Schrock, Yang-In Yim, Xufeng Wu, John A. Hammer
The paper identifies a myosin filament cage in polarized epithelial cells that drives planar division and asymmetric cleavage, and shows its disruption leads to orthogonal division and multiple lumens.
bioRxiv · Oct 28, 2026 · PreprintCell Biology