Kirsten Remmert

The paper identifies a myosin filament cage in polarized epithelial cells that drives planar division and asymmetric cleavage, and shows its disruption leads to orthogonal division and multiple lumens.

The paper uses phosphoproteomic data and KMEA to identify tumor-specific kinase activity in GEP-NETs, revealing potential therapeutic targets.

Imaging of mitochondria and lipid droplets (LDs) across mouse liver lobules shows fasting, not Western diet, expands mitochondria-LD contacts; PLIN5 phosphomutants tune contacts and lipid storage.

This study uses single-cell spatial proteomics to map human liver zonation patterns and shows their disruption in fibrosis.

The paper develops a perfusion circuit system to preserve tumor microenvironments in 3D patient-derived tumor models for up to 48 hours, enabling complex drug interrogations.

This study shows that myosin 18Aα recruits β-Pix to dendritic spines in Purkinje neurons, enhancing spine maturation through actin and myosin filament assembly.