Double-edged swords: Anthracyclines inhibit -1 programmed ribosomal frameshifting and restrict HCoV-OC43 infection but show cytotoxicity
Daniel Scheller, Md. Koushikul Islam, Karolis Vaitkevicius, Dmitriy Ignatov, Lisa Pettersson, Lena Lindgren, Niklas Arnberg, Jörgen Johansson
This study identifies three anthracyclines that reduce HCoV-OC43 infection by inhibiting -1 PRF but also show cytotoxicity.
bioRxiv · May 11, 2026 · PreprintMicrobiology