Multi-omic analysis of colorectal adenocarcinoma identifies a new subtype of myofibroblastic cancer-associated fibroblast expressing high level of B7-H3 and with poor prognosis value.
Maelle Picard, Arnaud Guillé, Pascal Finetti, Bernadette de Rauglaudre, Nadiya Belfil, Lenaïg Maescam, David Jérémie Birnbaum, François Bertucci, Émilie Mamessier
This study identifies a new subtype of myofibroblastic cancer-associated fibroblasts expressing high B7-H3 in colorectal cancer, which is associated with poor prognosis.
bioRxiv · Jun 30, 2025 · PreprintCancer Biology