Arnaud Guillé

This study shows TERT promotes liver tumors independently of telomere elongation, revealing molecular and metabolic features relevant to immunotherapy response.

This study analyzes the immune landscape of HR+/HER2- invasive lobular breast carcinomas using multi-omics approaches, revealing mobilized yet dysfunctional anti-tumor immunity due to impaired antigen presentation and immunosuppressive stroma.

This study identifies a new subtype of myofibroblastic cancer-associated fibroblasts expressing high B7-H3 in colorectal cancer, which is associated with poor prognosis.

The paper characterizes NPM1-mutated AML subtypes using epigenomic and transcriptomic data, revealing distinct clinical and molecular features based on H3K27me3 levels at the HIST1 cluster.

The paper shows that absence of Red1 and Hop1 recruitment prevents meiotic recombination on a chromosome arm containing the sex locus in Lachancea kluyveri, affecting genome evolution and fitness.