Higher baseline levels of fatty acid esters of hydroxy fatty acids do not further enhance the stimulatory effect of regular exercise on insulin sensitivity in obese mice
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinová, Petr Zouhar, Tomas Cajka, Ondřej Kuda, Lenka Rossmeislova, Martin Rossmeisl
This study investigates how exercise affects insulin sensitivity and FAHFA levels in obese mice, finding that chronic exercise improves insulin sensitivity in wild-type mice but not in ADTRP KO mice.
bioRxiv · Jun 11, 2026 · PreprintPhysiology