Author

Leo Swadling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Arlene H Sharpe· 1 shared Daniel C Douek· 1 shared Eleanor J Barnes· 1 shared Jernej Godec· 1 shared Kathleen B Yates· 1 shared Kevin Bi· 1 shared Nir YosefiD· 1 shared Paul Klenerman· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Arlene H Sharpe

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1 paper

Recent·Most cited

Targeted reconstruction of T cell receptor sequence from single cell RNA-sequencing links CDR3 length to T cell differentiation state

Shaked Afik, Kathleen B Yates, Kevin Bi, Samuel Darko, Jernej Godec, Ulrike Gerdemann, Leo Swadling, Daniel C Douek, Paul Klenerman, Eleanor J Barnes, Arlene H Sharpe, W. Nicholas Haining, Nir Yosef

This study develops TRAPeS, a tool to reconstruct TCR sequences from scRNA-seq data, and shows that CDR3 length correlates with T cell differentiation state in YFV-specific CD8+ T cells.

Nucleic Acids Research · Jul 17, 2017Peer-reviewedBioinformatics