Author

W. Nicholas Haining

Primary ORCID profile (0000-0001-7871-3762 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

W. Nicholas HainingiD2 papers · Arsenal Biosciences (United States)

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jernej Godec· 2 shared Arlene H Sharpe· 1 shared Daniel C Douek· 1 shared Eleanor J Barnes· 1 shared Felix Wu· 1 shared Jill P. Mesirov· 1 shared Kathleen B Yates· 1 shared Kevin Bi· 1 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Jernej Godec

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2 papers

Recent·Most cited

Targeted reconstruction of T cell receptor sequence from single cell RNA-sequencing links CDR3 length to T cell differentiation state

Shaked Afik, Kathleen B Yates, Kevin Bi, Samuel Darko, Jernej Godec, Ulrike Gerdemann, Leo Swadling, Daniel C Douek, Paul Klenerman, Eleanor J Barnes, Arlene H Sharpe, W. Nicholas Haining, Nir Yosef

This study develops TRAPeS, a tool to reconstruct TCR sequences from scRNA-seq data, and shows that CDR3 length correlates with T cell differentiation state in YFV-specific CD8+ T cells.

Nucleic Acids Research · Jul 17, 2017Peer-reviewedBioinformatics

A method for downstream analysis of gene set enrichment results facilitates the biological interpretation of vaccine efficacy studies

Yan Tan, Jernej Godec, Felix Wu, Pablo Tamayo, Jill P. Mesirov, W. Nicholas Haining

This paper introduces a method to refine gene set enrichment analysis results by identifying key gene groups, improving biological interpretation of vaccine efficacy studies.

bioRxiv · Apr 11, 2016 · PreprintBioinformatics