Author

Paul Klenerman

Primary ORCID profile (0000-0003-4307-9161 · 12 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Paul KlenermaniD12 papers · University of Oxford

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Nir YosefiD· 2 shared Alex Shalek· 1 shared Alexander van OudenaardeniD· 1 shared Alina Mirea· 1 shared Allon WagneriD· 1 shared Andrew Farmer· 1 shared Anna L. McNaughtoniD· 1 shared Anthony Phillipakis· 1 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioinformatics

Nir YosefORCID

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Author profile →

3 papers

Recent·Most cited

Human Herpes Virus 6 (HHV-6) - Pathogen or Passenger? A pilot study of clinical laboratory data and next generation sequencing

Colin Sharp, Tanya Golubchik, William F. Gregory, Anna L. McNaughton, Nicholas Gow, Mathyruban Selvaratnam, Alina Mirea, Dona Foster, Monique Andersson, Paul Klenerman, Katie Jeffery, Philippa C. Matthews

This study examines HHV-6 prevalence in clinical samples using PCR and NGS, finding 33% positivity in hematology patients and 20% detection via NGS in CSF and respiratory samples.

bioRxiv · Jul 5, 2018 · PreprintMicrobiology

Targeted reconstruction of T cell receptor sequence from single cell RNA-sequencing links CDR3 length to T cell differentiation state

Shaked Afik, Kathleen B Yates, Kevin Bi, Samuel Darko, Jernej Godec, Ulrike Gerdemann, Leo Swadling, Daniel C Douek, Paul Klenerman, Eleanor J Barnes, Arlene H Sharpe, W. Nicholas Haining, Nir Yosef

This study develops TRAPeS, a tool to reconstruct TCR sequences from scRNA-seq data, and shows that CDR3 length correlates with T cell differentiation state in YFV-specific CD8+ T cells.

Nucleic Acids Research · Jul 17, 2017Peer-reviewedBioinformatics

The Human Cell Atlas

Aviv Regev, Sarah A. Teichmann, Eric S. Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter Campbell, Piero Carninci, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, , the Human Cell Atlas Meeting Participants

The paper proposes the Human Cell Atlas project to catalog all human cell types through molecular profiling and connects this data with classical cellular descriptions.

bioRxiv · May 8, 2017 · PreprintCell Biology