The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson's disease
Carolin Gabbert, Leonie Blöbaum, Theresa Lüth, Inke Regina König, Amke Caliebe, Sebastian Sendel, Björn‐Hergen Laabs, Christine Klein, Joanne Trinh
The paper examines how polygenic scores and lifestyle factors influence age at onset in Parkinson's disease, finding that lifestyle factors have a larger impact than genetic variants.
Scientific Reports · Jun 25, 2024Peer-reviewedGenetic & Genomic Medicine