The ferroptosis mediator ACSL4 fails to prevent disease progression in mouse models of MASLD
Carolin Angendohr, Christiane Koppe, Diran Agaid Herebian, Anne T. Schneider, Leonie S. Keysberg, Michael T. Singer, Julian Gilljam, Matthias A. Dille, Johannes Georg Bode, Sebastian G. Doll, Marcus Conrad, Mihael Vucur, Tom Luedde
This study investigates whether ACSL4 deletion in liver cells prevents MASLD progression in mice but finds no significant differences compared to wild-type mice.
Hepatology Communications · May 16, 2025Peer-reviewedSystems Biology