Fine Tuning of Histone Demethylase KDM6A/B Improves the Development of Nuclear Transfer Embryo
Lei Yang, Lishuang Song, Xuefei Liu, Lige Bai, Guangpeng Li
This study shows that overexpressing KDM6A improves SCNT efficiency, while knocking down KDM6B facilitates ZGA and reduces ectopic Xist expression in reprogramming.
bioRxiv · Aug 14, 2018 · PreprintCell Biology