Author

Guangpeng Li

Inner Mongolia UniversityPrimary ORCID profile (0000-0001-8318-5853 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Guangpeng LiiD1 paper · Guangzhou Laboratory

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Lei YangiD· 2 shared Lishuang Song· 2 shared Xuefei LiuiD· 2 shared Anqi DiiD· 1 shared Chunling BaiiD· 1 shared Di WuiD· 1 shared Guanghua SuiD· 1 shared Li ZhangiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Lei YangORCID

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2 papers

Recent·Most cited

One-step generation of modified cattle and sheep from spermatid-like haploid stem cells

Lei Yang, Anqi Di, Lishuang Song, Xuefei Liu, Di Wu, Song Wang, Zhenting Hao, Lige Bu, Chunling Bai, Guanghua Su, Zhuying Wei, Li Zhang, Zhonghua Liu, Shaorong Gao, Guangpeng Li

This study generates gene-modified cattle and sheep using haploid stem cells with a modified iCHI approach that enhances embryo development.

Nature Biotechnology · Oct 7, 2025Peer-reviewedBioengineering

Fine Tuning of Histone Demethylase KDM6A/B Improves the Development of Nuclear Transfer Embryo

Lei Yang, Lishuang Song, Xuefei Liu, Lige Bai, Guangpeng Li

This study shows that overexpressing KDM6A improves SCNT efficiency, while knocking down KDM6B facilitates ZGA and reduces ectopic Xist expression in reprogramming.

bioRxiv · Aug 14, 2018 · PreprintCell Biology