Author

Lim Wei Wen

National University of Singapore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anissa Anindya WidjajaiD· 1 shared David CarlingiD· 1 shared Jessie Tan· 1 shared Joyce Wei Ting GohiD· 1 shared Shamini Guna ShekeraniD· 1 shared Sivakumar ViswanathaniD· 1 shared Stuart A. CookiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Anissa Anindya WidjajaORCID

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1 paper

Recent·Most cited

IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR in hepatocytes, the stroma and cancer cells

Anissa Anindya Widjaja, Joyce Wei Ting Goh, Sivakumar Viswanathan, Jessie Tan, Shamini Guna Shekeran, David Carling, Lim Wei Wen, Stuart A. Cook

This study identifies IL11's role in inhibiting LKB1/AMPK and activating mTOR through ERK/P90RSK, leading to metabolic dysfunction and fibrosis in multiple cell types and NASH in mice.

bioRxiv · Feb 10, 2022 · PreprintMolecular Biology