Small extracellular vesicular transfer of MYCN and glycolytic cargo coordinates metabolic and immunological reprogramming in neuroblastoma in vitro
Lin Ma, Mi Liu, Olga Piskareva
This study shows that MYCN-overexpressing neuroblastoma cells release extracellular vesicles containing MYCN and glycolytic cargo, which reprogram immune cells to support tumor growth.
bioRxiv · Apr 29, 2026 · PreprintCancer Biology