Structure-Based Calculation of Excipient Effects on the Viscosity ofConcentrated Antibody Solutions
John C. Shelley, Qing Chai, Lina Wu, Shaghayegh Vafaei, Mee Y. Shelley, Eric Feyfant, Jiangyan Feng, Mahlet A. Woldeyes, Volodymyr Babin, Jonathan Jou
This paper introduces a coarse-grained simulation method to predict the viscosity of antibody solutions and their response to excipients.
mAbs · Mar 21, 2026Peer-reviewedPharmacology & Toxicology