Ghrelin-Reactive Autoantibodies are elevated in Children with Prader-Willi Syndrome
Gabrielle Crisp, Ohn Nyunt, Lisa Chopin, Inge Seim, Mark Harris, Penny Jeffery
This study identifies elevated ghrelin-reactive autoantibodies in children with Prader-Willi Syndrome, which bind both orexigenic and non-orexigenic ghrelin isoforms, suggesting a potential therapeutic target for PWS and obesity.
bioRxiv · Dec 16, 2016 · PreprintPhysiology