A metagenomic thermostable monomeric meganuclease with novel specificity and unique palindromic 3-prime overhangs
Gol Mohammad Dorrazehi, Matthew Penner, Christina Athanasiou, Lise Boursinhac, Juan Carlos Mobarec, Carl I. Webster, Monika A. Papworth, Florian Hollfelder
The paper discovers a novel thermostable monomeric meganuclease from metagenomic data with unique DNA recognition and cleavage properties.
bioRxiv · Mar 20, 2026 · PreprintBiochemistry