Extracellular Vesicles Derived from L-MYC Neural Stem Cells Mediate Neuroprotection in 3D Models of Chemotherapy- and Radiation-Induced Neurotoxicity
Lance G. A. Nunes, Isabella Vasquez, Brecken Enright, Liv Chen, Sunita K. Patel, Russell C. Rockne, Stephanie M Yoon, Margarita Gutova
This study uses a 3D neural tissue model to show that extracellular vesicles from L-Myc neural stem cells promote recovery from chemotherapy- and radiation-induced neurotoxicity by modulating inflammatory and stress pathways.
bioRxiv · Oct 22, 2026 · PreprintCancer Biology