Margarita Gutova

This study uses a 3D neural tissue model to show that extracellular vesicles from L-Myc neural stem cells promote recovery from chemotherapy- and radiation-induced neurotoxicity by modulating inflammatory and stress pathways.

This study shows that intranasal LMNSC01 treatment reduces neuroimmune and neurovascular dysfunction after TBI by modulating ICAM-1 and CX3CL1 expression in both male and female rats.

The paper develops an agent-based model to predict neural stem cell migration in mouse brains using multi-fiber tractography, showing injection location affects distribution and suggesting factors like chemotaxis may be important.

This study uses a mathematical model to explore combination CAR T-cell treatments for glioblastoma, showing that early intervention and spatially targeted delivery are effective strategies.

This paper presents an organoid-based platform using L-MYC-immortalized human neural stem cells to model cerebral development in vitro, showing similar gene expression patterns to normal cortical development.

This study examines the structural and practical identifiability of compartment models used in DCE-MRI, showing that while all models are structurally identifiable, practical identifiability depends on data characteristics and noise levels.