Structure and iron-transporting mechanism of brain organic cation transporter 1
Jianan Chen, Shuhao Zhang, Wan Wei, Long Teng, Lei Tao, Kaixuan Gao, Bin Li, A.M. Edwards, Hao Fan, Xiangyu Liu, Ligong Chen
This study determines the structure of mouse BOCT1 and reveals its function as an independent iron transporter using cryo-EM and functional assays.
bioRxiv · Jun 28, 2025 · PreprintBiophysics