Recombinant Expression of Aldehyde Dehydrogenase 2 (ALDH2) in Escherichia coli Nissle 1917 for Oral Delivery in ALDH2-Deficient Individuals
Tim Ho, Catherine Chang, Justin C. Wu, Iris Huang, Leona Tsai, Justin Lin, Emily Tai, Caroline Chou, Justin Z. Yang, Yvonne Wei, Catherine Yeh, William Chen, Dylan Lu, Charlotte Chou, Longan Su, , Jude C. Clapper
This study produces recombinant ALDH2 in E. coli Nissle 1917 to reduce acetaldehyde levels in ALDH2-deficient individuals through oral delivery.
bioRxiv · Jun 21, 2019 · PreprintSynthetic Biology