Room Temperature Isothermal Colorimetric Padlock Probe Rolling Circle Amplification for Viral RNA Detection
Wilson Huang, Joyce Ting, Matthew Fang, Hannah Hsu, Jimmy Su, Tsuyoshi Misaki, Derek Chan, Justin Z. Yang, Ting-Yu Yeh, Kelly W. Yang, Vera Chien, Tiffany Huang, Andrew Chen, Claire Wei, Jonathan Hsu, Jude C. Clapper
This paper introduces a rapid, colorimetric, room-temperature viral RNA detection method using modified rolling circle amplification, showing high sensitivity and strain differentiation for SARS-CoV-2 and influenza viruses.
bioRxiv · Jun 12, 2020 · PreprintSynthetic Biology