Progenitor T cells drive chronic pulmonary type 2 inflammation
Radomir Kratchmarov, Xiaojiong Jia, Jun Nagai, Gaspar A. Pacheco, Alexander Perniss, M. A. Bell, Ersin Gül, Thornton W. Thompson, Hiroaki Hayashi, Shahab Saghaei, Caitlin Wong, Madeline Hastings, Kinan Alhallak, Juying Lai, Chunli Feng, , Patrick J. Brennan
The paper identifies tissue Th2 progenitors as a distinct cellular state that sustains chronic type 2 inflammation by self-renewal and effector differentiation.
Nature Immunology · Aug 20, 2026Peer-reviewedImmunology