Short Polysialic Acid Counteracts Age-Related Synaptic and Cognitive Deficits
Loris Frroku, Shaobo Jia, Stepan E. Aleshin, Srividya Makesh, Katrin Böhm, Aleksandra Alo, Timm Fiebig, Rita Gerardy‐Schahn, Markus Fendt, Hauke Thiesler, Alexander E. Dityatev
The paper shows that short polysialic acid (NANA12) improves cognitive and synaptic function in very old mice without altering neuronal structure or inflammation markers.
bioRxiv · Mar 13, 2025 · PreprintNeuroscience