Cutaneous suction-mediated transfection in mice for delivery of DNA-encoded vaccines and proteins
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar B. Kudchodkar, Nandita Chakrabarty Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow
This study develops and optimizes a cutaneous suction-mediated DNA transfection method in mice, demonstrating effective delivery of DNA vaccines and proteins with strong immune responses.
bioRxiv · Sep 10, 2025 · PreprintBioengineering