Modelling co-development between somites and neural tube with human Trunk-like Structures (hTLS)
Komal Makwana, Louise Tilley, Probir Chakravarty, Jamie Louise Thompson, Peter Baillie-Benson, Ignacio Rodríguez-Polo, Naomi Moris
The paper uses a human Trunk-like Structure (hTLS) model to study interactions between somites and neural tube during trunk development, showing endogenous signaling and dose-dependent ventralization.
Nature Cell Biology · Dec 1, 2025Peer-reviewedDevelopmental Biology